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The Downing Site is a major site of the University of Cambridge, located on Downing Street and Tennis Court Road, adjacent to Downing College. The Downing Site is the larger and newer of two city-centre science sites of the university (the other being the New Museums Site). Largely populated with utilitarian brick buildings dating from the 1930s, the more notable buildings include the Zoology Laboratory (1900–04), Sedgwick Museum of Earth Sciences (1904–11) and Downing Street entrance (1904–11).
Grade II Listed. Link
Wikipedia:
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Listed buildings and structures are officially designated as being of special architectural, historical or cultural significance. There are over half a million listed structures in the United Kingdom, covered by around 375,000 listings.
Listed status is more commonly associated with buildings or groups of buildings, however it can cover many other structures, including bridges, headstones, steps, ponds, monuments, walls, phone boxes, wrecks, parks, and heritage sites, and in more recent times a road crossing (Abbey Road) and graffiti art (Banksy 'Spy-booth') have been included.

In England and Wales there are three main listing designations;
Grade I (2.5%) - exceptional interest, sometimes considered to be internationally important.
Grade II* (5.5%) - particularly important buildings of more than special interest.
Grade II (92%) - nationally important and of special interest.

There are also locally listed structures (at the discretion of local authorities) using A, B and C designations.

In Scotland three classifications are also used but the criteria are different. There are around 47,500 Listed buildings.
Category A (8%)- generally equivalent to Grade I and II* in England and Wales
Category B (51%)- this appears generally to cover the ground of Grade II, recognising national importance.
Category C (41%)- buildings of local importance, probably with some overlap with English Grade II.

In Northern Ireland the criteria are similar to Scotland, but the classifications are:
Grade A (2.3%)
Grade B+ (4.7%)
Grade B (93%)

Read more at Wikipedia Link